The return of Hanover wide receiver Daniel Passafiume from illness highlights the 2012 preseason D3football.com All-American team.
| Pos. | First Team | Second Team |
| Offense | ||
| QB | Garrett Meador, Sr., Wheaton (Ill.) | Nate Wara, Sr., UW-Oshkosh |
| RB | Germany Woods, Jr., Heidelberg | Darius Wilson, Sr., Mary Hardin-Baylor |
| RB | Shawn Morris, Sr., Birmingham-Southern | Trevor Manuel, Sr., Huntingdon |
| WR | Daniel Passafiume, Sr., Hanover | Tyler Huber, Sr., UW-Whitewater |
| WR | Adam Kniffin, Sr., Puget Sound | Trey Fairchild, Sr., Otterbein |
| TE | Billy Chapman, Sr., Middlebury | Adam Carl, Jr., Augsburg |
| T | Antonio Tate, Sr., Mount Union | Jace Werkheiser, Jr., North Central (Ill.) |
| G | John LaVelle, Sr., Delaware Valley | Nick Schultz, Sr., Franklin |
| C | Curtis James, Sr., St. Thomas | Richard Skaife, Sr., Dubuque |
| G | Michael Coles, Sr., Mary Hardin-Baylor | Christian Emezie, Sr., Salisbury |
| T | Weston Kitley, Sr., Wabash | Armand Jenifer, Jr., Johns Hopkins |
| Defense | ||
| DE | Frank Weymiller, Sr., Coe | Charles Dieseul, Sr., Mount Union |
| DT | D.J. Chappell, Sr., Huntingdon | Rian Younker, Sr., Cal Lutheran |
| DT | Tyler Steele, Sr., Linfield | Mike Raplee, Sr., Alfred |
| DE | Ben Lockton, Sr., Benedictine | Loussaint Minett, Jr., UW-Whitewater |
| LB | Devan Sproles, Sr., Emory and Henry | Dan Avento, Jr., Montclair State |
| LB | Javicz Jones, Sr., Mary Hardin-Baylor | Mike Hendrick, Sr., Knox |
| LB | Nick Bricker, Jr., TCNJ | Devin Worthington, Jr., Hobart |
| CB | Troy Sant, Sr., St. John Fisher | Zach Morgan, Jr., Hampden-Sydney |
| S | Jake Pelton, Sr., Washington & Lee | Zach Autenrieb, Sr., Thomas More |
| S | Nick Driskill, Sr., Mount Union | Demetreus Johnson, Sr., Coe |
| CB | Josh Mitchell, Sr., North Central (Ill.) | Noah Timm, Sr., UW-Whitewater |
| Special teams | ||
| K | Allen Cain, Sr., Texas Lutheran | Jacob Gahart, Sr., Ripon |
| P | Christian Hallingstad, Sr., UW-La Crosse | Kyle Trella, Sr., Trinity (Texas) |
| RET | Mike Graham, Sr., Western New England | Taylor Wagner, Sr., DePauw |